Keywords
adenitis
generalized periodontitis
MMP-8
LL-37
Lactoferrin
How to Cite
Abstract
According to WHO, up to 75% of the population in different regions of the world are affected by the partial absence of teeth. Clinical observations show that in most cases, the cause of adentias is generalized periodontitis. According to researchers, from 5 to 20% of the population suffers from severe periodontitis, and from the mild to moderate periodontitis, the majority of adults. Moreover, periodontitis is associated with other serious conditions such as coronary heart disease, head and neck carcinoma, and chronic obstructive pulmonary disease.
The aim of our study was to establish prognostically significant molecular biochemical criteria in the planning of implantological and orthopedic treatment of patients with periodontal tissue disorders and defects in the dentition.
40 patients were selected for the study. Among them, 10 healthy patients comprised the control group and 30 major patients with periodontal tissue disorders. Among them are 10 patients with grade I, 10 patients with grade II, 10 patients with grade III parodontitis and dentition defects.
Determination of the level of biological markers of the oral fluid is a promising diagnostic method, does not require special training from a dentist, is a minimally invasive technique, and will allow to evaluate the current state of prosthetic bed tissues, which will allow rational planning of the type of orthopedic rehabilitation of dental patients.
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